亚博安全有保障

 
刘竞男
发布人:网站管理员  发布时间:亚博安全有保障-03-10   浏览次数:1193


1.个人简介:

   刘竞男博士,副教授,生物学专业硕士生导师。主要以果蝇等模式动物,研究代谢性疾病的发生和病理机制;研究媒介昆虫免疫与病原感染机制以及防控新技术。主持国家自然科学基金面上项目2项,研究成果以第一作者或通讯作者(含共一或共通讯)发表在Science,Cell Reports,PNAS,Cell Death & Disease等学术期刊上。

  联系方式:jnliu@shnu.edu.cn

教育经历:

 2002 – 2006 博士,中国科亚博安全有保障合肥物质科亚博安全有保障等离子科学研究所

 1997 – 2000 硕士,安徽农业大学,中国虫生真菌研究中心

 1993 – 1997 学士,大连工业大学

工作经历:

 亚博安全有保障-至今,上海师范大学,亚博安全有保障,副教授

 2016-亚博安全有保障,上海科技大学,生命科学与技术亚博安全有保障,副研究员

 2013-2016,中国科学亚博安全有保障上海营养与健康研究所,副研究员

 2010-2013,美国马里兰大学,药亚博安全有保障,博士后

 2008-2009,美国马里兰大学,昆虫系,博士后

 2000-2007,安徽大学,亚博安全有保障,讲师


2.主要研究方向

(1)以果蝇等模式动物,研究代谢紊乱疾病的发生和病理机制。

(2)媒介昆虫免疫与病原感染机制。

(3)研发干预代谢疾病和蚊媒防控的新技术。


3.代表性科研项目

1) “CTP合成酶动态组装细胞蛇调控果蝇脂质代谢稳态的生理功能和机制”,家自然科学基金面上项目,1/2021-12/亚博安全有保障,主持人;

2) “果蝇脂肪体中内质网应激IRE1通路的代谢调控作用与机制 ”,家自然科学基金面上项目,1/2015-12/2018,主持人;


4.代表论文

1Wang GD*, Joel Vega-Rodriguez*, Abdoulaye Diabate*, Liu JN* (Co-first author), Cui CL, Charles Nignan, Dong L, Li F, Cheick Oumar Ouedrago, Abdoul Malik Bandaogo, Péguédwindé Simon Sawadogo, Hamidou Maiga,Thiago Luiz Alves e Silva, Tales Vicari Pascini, Wang SB, Jacobs-Lorena M. Anopheles swarming and mating are coordinately governed by clock genes, light and temperature. Science. 2021, 371(6527): 411-415. doi: 10.1126/science.abd4359.

2Cui CL, Wang Y, Li YF, Sun PL, Jiang JY, Zhou HN, Liu JN#(Co-corresponding author), Wang, SB#. Expression of mosquito miRNAs in an entomopathogenic fungus induces pathogen-mediated host RNA interference and increases fungal efficacy. Cell Reports. 2022, 25;41(4):111527. doi: 10.1016/j.celrep.2022.111527.

3Liu JN*, ZhangYB*, Zhou YF, Wang Q-Q, Ding K, Zhao SY, Lu P, and Liu J-L. Cytoophidia coupling adipose architecture and metabolism.Cellular and Molecular Life Science. 2022,79(10):534. doi: 10.1007/s00018-022-04567-w.

4Liu JN, Wang X, Ma R, Li TX, Guo G, Ning B, Moran TH, and Smith W. W. AMPK signaling mediates synphilin-1-induced hyperphagia and obesity in Drosophila. Journal of Cell Science. 2021,134(3):jcs247742. doi: 10.1242/jcs.247742.

5Yan C, Liu JJ, Gao J, Sun Y, Zhang L, Song HY, Xue L, Zhan LX, Gao GJ, Ke ZJ, Liu Y#and Liu JN#. IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson’s disease. Cell Death & Disease. 2019,10(11): 800. doi: 10.1038/s41419-019-2039-6.

6Zhou YF*Liu JN*(Co-first author)Zhang YBLiu J-L. Drosophila intestinal homeostasis requires CTP synthase.Experimental Cell Research.2021,408(1):112838. doi: 10.1016/j.yexcr.2021.112838.

7Zhang H*, Liu JN* (Co-first author), Li R C, Woman B, Kohanski RA, and Pick L. Deletion of Drosophila insulin-like peptides causes growth defects and metabolic abnormalities. PNAS.2009,106:19617-19622.

8Liu JN, Li TX, Thomas JM, Pei Z, Jiang H, Engelender S, Ross CA and Smith WW. Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson’s disease models. Human Molecular Genetics. 2016,15; 25(4):672-80.

9Liu JN, Li TX, Yang DJ, Ma R, Moran TH, and Smith WW.Synphilin-1 alters metabolic homeostasis in a novel Drosophila obesity model. International Journal of Obesity. 2012,36(12):1529-36.

10Zhao P, Huang P,Xu TF, Xiang XX, Sun Y, Liu JN, Song W, Liu Y. Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila.iScience.2021, 24(8):102819. doi: 10.1016/j.isci.2021.102819.

11Cui CL, Wang Y, Liu JN, Zhao J, Sun PL, Wang SB. A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection. Nature Communications. 2019, 10:4298. doi: 10.1038/s41467-019-12323-1.

12Liu Y, Shao ML, Wu Y, Yan C, Jiang S, Liu JN, Dai JL, Yang L, Li J, Jia WP, Rui L, and Y. Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses. Journal of Hepatology.2015, 62(3):590-8.


更新时间:亚博安全有保障年3月



 
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